2244986-40-9
2244986-40-9
Chemical Structure
CDK12/13 ligand 1
- CAS No.: 2244986-40-9
- Formula:C26H26BrN5O
- Molecular Weight:504.42
InChIKey: FMVSITGZOKXXOA-HCGLCNNCSA-N
SMILES: O=C(N([C@@H]1CC[C@H](CC1)NC2=CC=C(C=N2)C#N)C3=CC=C(Br)C=C3)NCC4=CC=CC=C4
Biological Activity: ALK-IN-29 (compound 4c) has a certain inhibitory effect on tyrosine protein kinases ALK, CDK2/CyclinE1 and FAK, among which the strongest inhibitory effect on ALK kinase is 40.63% at a concentration of 10 μM. ALK-IN-29 can be used for anti-cancer research[1].
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CDK12/13 ligand 1 | ALK-IN-29 (compound 4c) has a certain inhibitory effect on tyrosine protein kinases ALK, CDK2/CyclinE1 and FAK, among which the strongest inhibitory effect on ALK kinase is 40.63% at a concentration of 10 μM. ALK-IN-29 can be used for anti-cancer research. | |||||||||||||||||||||
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References
Keywords
