3027967-95-6
3027967-95-6
Chemical Structure
DDR1/2 IN-4
- CAS No.: 3027967-95-6
- Formula:C23H20F3N7O
- Molecular Weight:467.45
InChIKey: LQDLTPFDISUEPV-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)(F)F)=CN=C1)C2=CC=C(C)C(NC3CN(C4=C5C=NC=CN5N=C4)C3)=C2
Biological Activity: DDR1/2 IN-4 (Compound 37) is a selective dual DDR1 and DDR2 kinase inhibitor, with a pKi of 8.6 for DDR1 and a pKi of 8.2 for DDR2. DDR1/2 IN-4 functionally inhibits the kinase activities of DDR1 and DDR2. DDR1/2 IN-4 inhibits the release of MCP-1. DDR1/2 IN-4 can be used in studies related to idiopathic pulmonary fibrosis[1].
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DDR1/2 IN-4 | DDR1/2 IN-4 (Compound 37) is a selective dual DDR1 and DDR2 kinase inhibitor, with a pKi of 8.6 for DDR1 and a pKi of 8.2 for DDR2. DDR1/2 IN-4 functionally inhibits the kinase activities of DDR1 and DDR2. DDR1/2 IN-4 inhibits the release of MCP-1. DDR1/2 IN-4 can be used in studies related to idiopathic pulmonary fibrosis. | |||||||||||||||||||||
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References
Keywords
