Dohh - deoxyhypusine hydroxylase/monooxygenase Gene

Also Known as Hlrc1; 1110033C18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 102115

Summary

Predicted to enable deoxyhypusine monooxygenase activity and iron ion binding activity. Acts upstream of or within peptidyl-lysine modification to peptidyl-hypusine. Is expressed in nervous system; retina; and skeletal muscle. Orthologous to human DOHH (deoxyhypusine hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Dohh Products (1)

mRNA Protein Name
NM_133964.3 NP_598725.2 deoxyhypusine hydroxylase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables deoxyhypusine monooxygenase activity IMP
IMP: Inferred from mutant phenotype
24832488 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within peptidyl-lysine modification to peptidyl-hypusine IMP
IMP: Inferred from mutant phenotype
24832488 MGI
involved in peptidyl-lysine modification to peptidyl-hypusine IMP
IMP: Inferred from mutant phenotype
24832488 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

deoxyhypusine hydroxylase

  • HEAT-like (PBS lyase) repeat containing 1

  • deoxyhypusine dioxygenase

  • deoxyhypusine monooxygenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174461 PROTAC PI3Kα degrader-1 Degrader 99.21% Unkown
HY-121722 Deoxyhypusine / Unkown
HY-153705 BTK-IN-25 Inhibitor / Unkown
HY-169307 BTK-IN-38 Inhibitor / Unkown
HY-172217 DNMT1-IN-5 / Unkown
HY-RS03932 DOHH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126171 Hypusine / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dohh NCBI NCBI:83475