TUBGCP3 - tubulin gamma complex associated protein 3 Gene

Also Known as 104p; ALP6; GCP3; Spc98; SPBC98; Spc98p; Grip104

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10426

About TUBGCP3

Cytogenetic location: 13q34 Genomic coordinates (GRCh38): 13:112,485,011-112,605,630 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 203 orthologues and 4 paralogues. Ubiquitous expression in testis (RPKM 8.5), ovary (RPKM 6.0) and 25 other tissues.

Summary

Enables gamma-tubulin binding activity. Predicted to be involved in meiotic cell cycle; microtubule Cytoskeleton organization; and mitotic cell cycle. Located in cytoplasm and microtubule Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

TUBGCP3 Products (4)

mRNA Protein Name
NM_001286277.2 NP_001273206.1 gamma-tubulin complex component 3 isoform 2
NM_001286278.2 NP_001273207.1 gamma-tubulin complex component 3 isoform 3
NM_001286279.2 NP_001273208.1 gamma-tubulin complex component 3 isoform 4
NM_006322.6 NP_006313.1 gamma-tubulin complex component 3 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables gamma-tubulin binding IDA
IDA: Inferred from direct assay
9566969 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
9566969 GOA
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
9566969 GOA
located in centrosome IDA
IDA: Inferred from direct assay
9566969 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
9566969 GOA
located in polar microtubule IDA
IDA: Inferred from direct assay
9566969 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TUBGCP3 Protein Structure

Spc97_Spc98

Spc97_Spc98: Spc97 / Spc98 family (253 - 763)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 907 a.a.
Protein Preferred Names Protein Names

gamma-tubulin complex component 3

  • gamma-ring complex protein 104 kDa

Related Diseases

Diseases Alias
Pituitary Adenoma 3, Multiple Types

  • PITA3

  • Pituitary Adenoma 3, Multiple Types, Somatic

  • Pituitary Adenoma 3
Combined Oxidative Phosphorylation Deficiency 20

  • COXPD20

  • Combined Oxidative Phosphorylation Defect Type 20

  • Oxidative Phosphorylation Deficiency, Combined, Type 20
Gluten Allergy

  • Allergy To Gluten

  • Gluten Allergic Reaction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15263 TUBGCP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TUBGCP3 VGNC VGNC:79153
Mus musculus TUBGCP3 MGD MGI:2183752
Canis familiaris TUBGCP3 VGNC VGNC:47993
Felis catus TUBGCP3 VGNC VGNC:66705
Rattus norvegicus TUBGCP3 RGD RGD:1305726
Bos taurus TUBGCP3 VGNC VGNC:36513