LIPJ - lipase family member J Gene

Also Known as LIPL1; bA425M17.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 142910

About LIPJ

Cytogenetic location: 10q23.31 Genomic coordinates (GRCh38): 10:88,582,907-88,623,184 (from NCBI)

This gene has 3 transcripts (splice variants), 114 orthologues and 5 paralogues. Broad expression in testis (RPKM 1.7), thyroid (RPKM 0.3) and 20 other tissues.

Summary

Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be involved in lipid catabolic process. Predicted to be active in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

LIPJ Products (2)

mRNA Protein Name
NM_001010939.3 NP_001010939.2 lipase member J isoform 1
NM_001394640.1 NP_001381569.1 lipase member J isoform 2

LIPJ Protein Structure

Abhydro_lipase

Abhydro_lipase: Partial alpha/beta-hydrolase lipase region (3 - 65)

Abhydrolase_1

Abhydrolase_1: alpha/beta hydrolase fold (80 - 351)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
Protein Preferred Names Protein Names

lipase member J

  • lipase J

Related Diseases

Diseases Alias
Lysosomal And Lipase Deficiency
Cerebrooculofacioskeletal Syndrome 4
  • COFS4

  • Cerebro-Oculo-Facio-Skeletal Syndrome 4

  • Cofs Syndrome

  • Cerebrooculofacioskeletal Syndrome, Type 4

Mixed Sleep Apnea
  • Complex Sleep Apnea

  • Sleep Apnea, Mixed Central And Obstructive

Lysosomal Acid Lipase Deficiency
  • Wolman Disease

  • Cholesteryl Ester Storage Disease

  • Lal Deficiency

  • Lipa Deficiency

  • Cholesterol Ester Storage Disease

  • CESD

  • Cholesterol Ester Hydrolase Deficiency

  • Acid Lipase Deficiency

  • Acid Esterase Deficiency

  • Familial Xanthomatosis

  • Wolman Xanthomatosis

  • Wolman'S Disease

  • Wolman'S Or Triglyceride Storage Type Iii Disease

  • Xanthomatosis, Familial

  • Liposomal Acid Lipase Deficiency, Wolman Type

  • Familial Visceral Xanthomatosis

  • Primary Familial Xanthomatosis

  • Primary Familial Xanthomatosis With Adrenal Calcification

  • Acid Lipase Disease

  • WOD

  • Acid Cholesteryl Ester Hydrolase Deficiency, Type 2

Fusariosis
  • Fusarium Infection

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus LIPJ VGNC VGNC:30906
Macaca mulatta LIPJ VGNC VGNC:74333
Canis familiaris LIPJ VGNC VGNC:42699
Felis catus LIPJ VGNC VGNC:63241
Rattus norvegicus LIPJ RGD RGD:2321667