Islr2 - immunoglobulin superfamily containing leucine-rich repeat 2 Gene

Also Known as Linx; Mbu-3; mKIAA1465; B930052A04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 320563

Summary

Involved in positive regulation of axon extension. Located in cell surface. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2). [provided by Alliance of Genome Resources, Apr 2022]

Islr2 Products (8)

mRNA Protein Name
NM_001161535.1 NP_001155007.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform a
NM_001161536.1 NP_001155008.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_001161537.1 NP_001155009.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_001161538.1 NP_001155010.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_001161539.1 NP_001155011.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_001161540.1 NP_001155012.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_001161541.1 NP_001155013.1 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor
NM_177193.5 NP_796167.2 immunoglobulin superfamily containing leucine-rich repeat protein 2 isoform b precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19755105 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of axon extension IMP
IMP: Inferred from mutant phenotype
19755105 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19755105 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

immunoglobulin superfamily containing leucine-rich repeat protein 2

  • leucine-rich repeat domain and immunoglobulin domain containing axon extension protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06934 ISLR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Islr2 NCBI NCBI:57611