Slc23a2 - solute carrier family 23 member 2 Gene

Also Known as SVCT2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 50622

Summary

Enables L-ascorbate:sodium symporter activity and L-ascorbic acid transmembrane transporter activity. Involved in several processes, including L-ascorbic acid transmembrane transport; cellular response to ethanol; and positive regulation of dendrite extension. Located in basal plasma membrane and cytoplasm. Is integral component of plasma membrane. Orthologous to human SLC23A2 (solute carrier family 23 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc23a2 Products (1)

mRNA Protein Name
NM_017316.2 NP_059012.2 solute carrier family 23 member 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-ascorbate:sodium symporter activity IDA
IDA: Inferred from direct assay
10331392 RGD
enables L-ascorbate:sodium symporter activity IMP
IMP: Inferred from mutant phenotype
10331392 RGD
enables L-ascorbic acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
18668520 RGD
Biological Process GO Annotation Evidence References Source
involved in L-ascorbic acid metabolic process IMP
IMP: Inferred from mutant phenotype
10331392 RGD
involved in L-ascorbic acid transmembrane transport IDA
IDA: Inferred from direct assay
18668520 RGD
involved in L-ascorbic acid transmembrane transport IMP
IMP: Inferred from mutant phenotype
10331392 RGD
involved in cellular response to ethanol IEP
IEP: Inferred from expression pattern
27085842 RGD
involved in positive regulation of dendrite extension IMP
IMP: Inferred from mutant phenotype
27085842 RGD
involved in response to oxidative stress IEP
IEP: Inferred from expression pattern
12887688 RGD
Cellular Component GO Annotation Evidence References Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
18668520 RGD
located in cytoplasm IDA
IDA: Inferred from direct assay
18668520 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

solute carrier family 23 member 2

  • Na(+)/L-ascorbic acid transporter 2

  • sodium-coupled ascorbic acid transporter 2

  • sodium-dependent vitamin C transporter 2

  • solute carrier family 23 (ascorbic acid transporter), member 2

  • solute carrier family 23 (nucleobase transporters), member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13081 SLC23A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13082 SLC23A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc23a2 NCBI NCBI:9962