Itga9 - integrin alpha 9 Gene

Also Known as (alpha)9; D130073C02; D9Ertd428e; 2610002H11Rik; 6720458D17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 104099

Summary

Predicted to enable metal ion binding activity. Acts upstream of or within neutrophil chemotaxis. Located in basal plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; skin; and vascular system. Used to study congenital chylothorax. Human ortholog(s) of this gene implicated in cerebral infarction; hypertension; and pancreatic Cancer. Orthologous to human ITGA9 (Integrin subunit alpha 9). [provided by Alliance of Genome Resources, Apr 2022]

Itga9 Products (2)

mRNA Protein Name
NM_001113514.1 NP_001106986.1 integrin alpha-9 isoform b
NM_133721.2 NP_598482.2 integrin alpha-9 isoform a precursor
Molecular Function GO Annotation Evidence References Source
enables integrin binding involved in cell-matrix adhesion IDA
IDA: Inferred from direct assay
22654117 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within neutrophil chemotaxis IGI
IGI: Inferred from genetic interaction
21321126 MGI
Cellular Component GO Annotation Evidence References Source
located in basal plasma membrane IDA
IDA: Inferred from direct assay
7534781 MGI
part of integrin alpha9-beta1 complex IDA
IDA: Inferred from direct assay
22654117 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-9

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga9 NCBI NCBI:3680