Arsb - arylsulfatase B Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25227

Summary

Enables sulfuric ester hydrolase activity. Involved in several processes, including positive regulation of neuron projection development; response to estrogen; and response to methylmercury. Located in several cellular components, including Golgi apparatus; lysosome; and rough endoplasmic reticulum. Used to study mucopolysaccharidosis VI. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B). [provided by Alliance of Genome Resources, Apr 2022]

Arsb Products (1)

mRNA Protein Name
NM_033443.1 NP_254278.1 arylsulfatase B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables sulfuric ester hydrolase activity IDA
IDA: Inferred from direct assay
2884099 RGD
Biological Process GO Annotation Evidence References Source
involved in autophagy IDA
IDA: Inferred from direct assay
8037 RGD
involved in positive regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
24311516 RGD
involved in response to estrogen IDA
IDA: Inferred from direct assay
15040 RGD
involved in response to methylmercury IDA
IDA: Inferred from direct assay
1682910 RGD
involved in response to nutrient IDA
IDA: Inferred from direct assay
2290353 RGD
involved in response to pH IDA
IDA: Inferred from direct assay
6137211 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19536613 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase B

  • ASB

  • Arylsulfatase B (MPS VI)

  • G4S

  • N-acetylgalactosamine-4-sulfatase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70186 Arylsulfatase B / Unkown
HY-RS00729 ANKRD44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01035 ARSB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13385 SLURP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsb NCBI NCBI:411