Pex5l - peroxisomal biogenesis factor 5-like Gene

Also Known as Pex2; TRIP8b; Trjip8b

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 286937

Summary

Enables intracellular cyclic nucleotide activated cation channel activity and small GTPase binding activity. Involved in positive regulation of corticotropin secretion; regulated exocytosis; and regulation of cAMP-mediated signaling. Located in cell tip and perinuclear region of cytoplasm. Part of intracellular cyclic nucleotide activated cation channel complex. Orthologous to human PEX5L (peroxisomal biogenesis factor 5 like). [provided by Alliance of Genome Resources, Apr 2022]

Pex5l Products (10)

mRNA Protein Name
NM_001393823.1 NP_001380752.1 PEX5-related protein isoform 2
NM_001393824.1 NP_001380753.1 PEX5-related protein isoform 3
NM_001393825.1 NP_001380754.1 PEX5-related protein isoform 4
NM_001393826.1 NP_001380755.1 PEX5-related protein isoform 5
NM_001393827.1 NP_001380756.1 PEX5-related protein isoform 6
NM_001393828.1 NP_001380757.1 PEX5-related protein isoform 7
NM_001393829.1 NP_001380758.1 PEX5-related protein isoform 8
NM_001393830.1 NP_001380759.1 PEX5-related protein isoform 9
NM_001393831.1 NP_001380760.1 PEX5-related protein isoform 6
NM_173152.3 NP_775175.2 PEX5-related protein isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables intracellularly cyclic nucleotide-activated monoatomic cation channel activity IDA
IDA: Inferred from direct assay
19555650 RGD
enables small GTPase binding IPI
IPI: Inferred from physical interaction
11278749 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of corticotropin secretion IDA
IDA: Inferred from direct assay
11278749 RGD
involved in regulated exocytosis IDA
IDA: Inferred from direct assay
11278749 RGD
involved in regulation of cAMP-mediated signaling IDA
IDA: Inferred from direct assay
19555650 RGD
Cellular Component GO Annotation Evidence References Source
located in cell tip IDA
IDA: Inferred from direct assay
11278749 RGD
part of intracellular cyclic nucleotide activated cation channel complex IDA
IDA: Inferred from direct assay
19555650 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
11278749 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

PEX5-related protein

  • PEX5-like protein

  • TPR-containing Rab8b-interacting protein

  • peroxin 2

  • peroxin-5-related protein

  • pex5Rp

  • tetratricopeptide repeat-containing Rab8b-interacting protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10352 PEX5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pex5l NCBI NCBI:51555