Tbx6 - T-box transcription factor 6 Gene

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including cell fate specification; heart development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of neuron maturation; regulation of gene expression; and somite rostral/caudal axis specification. Predicted to be located in chromatin and nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human TBX6 (T-box transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]