227321-12-2
227321-12-2
Chemical Structure
MCT1-IN-2
- CAS 番号: 227321-12-2
- Formula:C25H29N3O2S
- Molecular Weight:435.58
IUPAC Name: 7-((3-hydroxypropyl)thio)-4-isobutyl-2-methyl-6-(naphthalen-1-ylmethyl)-2,6-dihydro-1H-pyrrolo[3,4-d]pyridazin-1-one
InChIKey: VDAVMXLEMHVXOG-UHFFFAOYSA-N
SMILES: O=C1C2=C(SCCCO)N(CC3=C4C=CC=CC4=CC=C3)C=C2C(CC(C)C)=NN1C
Biological Activity: MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity[1][2].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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MCT1-IN-2 | 99.88% | MCT1-IN-2 is a potent monocarboxylate transporter 1 (MCT1) inhibitor. MCT1-IN-2 has anti-cancer activity. | ||||||||||||||||||||
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References
- [1]. Clare M Murray, et al. Monocarboxylate transporter MCT1 is a target for immunosuppression. Nat Chem Biol. 2005 Dec;1(7):371-6. [Content Brief]
- [2]. Hui Wang, et al. Synthesis and structure-activity relationships of pteridine dione and trione monocarboxylate transporter 1 inhibitors. J Med Chem. 2014 Sep 11;57(17):7317-24. [Content Brief]
Keywords
