Clcn7 - chloride channel, voltage-sensitive 7 Gene

Predicted to enable chloride transmembrane transporter activity. Predicted to be involved in response to pH. Predicted to act upstream of or within ion transport. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including early conceptus; heart and pericardium; nervous system; oocyte; and submandibular gland primordium. Used to study autosomal dominant osteopetrosis 2 and autosomal recessive osteopetrosis 4. Human ortholog(s) of this gene implicated in autosomal dominant osteopetrosis 2 and autosomal recessive osteopetrosis 4. Orthologous to human CLCN7 (chloride voltage-gated channel 7). [provided by Alliance of Genome Resources, Apr 2022]