Gja8 - gap junction protein, alpha 8 Gene

Also Known as Cx50; Cxnl

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 29601

Summary

Enables identical protein binding activity. Contributes to gap junction channel activity. Involved in cell-cell signaling. Is integral component of membrane. Part of connexin complex. Used to study cataract; cataract 1 multiple types; and microphthalmia. Human ortholog(s) of this gene implicated in cataract and cataract 1 multiple types. Orthologous to human GJA8 (Gap Junction Protein alpha 8). [provided by Alliance of Genome Resources, Apr 2022]

Gja8 Products (1)

mRNA Protein Name
NM_153465.2 NP_703195.2 gap junction alpha-8 protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
contributes to gap junction channel activity IDA
IDA: Inferred from direct assay
16123426 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
16123426 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16123426 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in cell-cell signaling IDA
IDA: Inferred from direct assay
16123426 RGD
involved in regulation of catalase activity IMP
IMP: Inferred from mutant phenotype
27871290 RGD
involved in regulation of glutathione peroxidase activity IMP
IMP: Inferred from mutant phenotype
27871290 RGD
involved in regulation of granulocyte macrophage colony-stimulating factor production IMP
IMP: Inferred from mutant phenotype
27871290 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
part of connexin complex IDA
IDA: Inferred from direct assay
16123426 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gap junction alpha-8 protein

  • connexin l

  • connexin-50

  • gap junction membrane channel protein alpha 8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05445 GJA8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Gja8 NCBI NCBI:2703