Tbx2 - T-box transcription factor 2 Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cardiac jelly development; circulatory system development; and embryonic morphogenesis. Predicted to act upstream of or within several processes, including animal organ development; muscle cell fate determination; and ureteric peristalsis. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in vertebral anomalies and variable endocrine and T-cell dysfunction. Orthologous to human TBX2 (T-box transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]