GRAMD1C - GRAM domain containing 1C Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 54762

About GRAMD1C

This gene has 15 transcripts (splice variants), 218 orthologues and 4 paralogues. Broad expression in kidney (RPKM 8.8), testis (RPKM 8.7) and 21 other tissues.

Summary

Predicted to enable Cholesterol binding activity and Cholesterol transfer activity. Predicted to be involved in cellular response to Cholesterol. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GRAMD1C Products (2)

mRNA Protein Name
NM_001172105.2 NP_001165576.1 protein Aster-C isoform 2
NM_017577.5 NP_060047.3 protein Aster-C isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GRAMD1C Protein Structure

GRAM

GRAM: GRAM domain (70 - 135)

  • 0
  • 200
  • 400
  • 600
  • 662 a.a.
Protein Preferred Names Protein Names

protein Aster-C

  • GRAM domain-containing protein 1C

GRAMD1C Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
GRAMD1C Q8IYS0 CD151 Homo sapiens P48509
Y2H Array
29892012
Intra
GRAMD1C Q8IYS0 CD151 Homo sapiens P48509
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Generalized Atherosclerosis

  • Generalised Atherosclerosis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05774 GRAMD1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Rattus norvegicus GRAMD1C RGD RGD:1305433
Felis catus GRAMD1C VGNC VGNC:62703
Canis familiaris GRAMD1C VGNC VGNC:41467
Mus musculus GRAMD1C MGD MGI:2443024
Bos taurus GRAMD1C VGNC VGNC:29624
Macaca mulatta GRAMD1C VGNC VGNC:73007
Others GRAMD1C NCBI