RETSAT - retinol saturase Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 54884

About RETSAT

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:85,341,955-85,354,528 (from NCBI)

This gene has 7 transcripts (splice variants), 219 orthologues and 2 paralogues. Broad expression in fat (RPKM 182.7), duodenum (RPKM 78.0) and 17 other tissues.

Summary

Predicted to enable all-trans-retinol 13,14-reductase activity. Predicted to be involved in retinol metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

RETSAT Products (1)

mRNA Protein Name
NM_017750.4 NP_060220.3 all-trans-retinol 13,14-reductase precursor

RETSAT Protein Structure

NAD_binding_8

NAD_binding_8: NAD(P)-binding Rossmann-like domain (72 - 124)

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  • 610 a.a.
Protein Preferred Names Protein Names

all-trans-retinol 13,14-reductase

  • PPAR-alpha-regulated and starvation-induced gene protein

関連疾患

Diseases Alias
Macular Degeneration, Age-Related, 10
  • ARMD10

  • Age Related Macular Degeneration 10

  • Macular Degeneration, Age-Related, Type 10

Gastric Cardia Carcinoma
  • Carcinoma Of Cardia Of Stomach

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta RETSAT VGNC VGNC:97818
Mus musculus RETSAT MGD MGI:1914692
Canis familiaris RETSAT VGNC VGNC:45486
Rattus norvegicus RETSAT RGD RGD:628802
Bos taurus RETSAT VGNC VGNC:33881
Felis catus RETSAT VGNC VGNC:81170
Others RETSAT NCBI