108979-07-3
Chemical Structure
FKB04
- CAS No.: 108979-07-3
- Formula:C17H15BrO4
- Molecular Weight:363.20
InChIKey: HULOKJPQNJZXKY-VOTSOKGWSA-N
SMILES: BrC1=CC(/C=C/C(C2=C(C=C(C=C2O)OC)OC)=O)=CC=C1
Biological Activity: FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanism in liver cancer cells, leading to T-loop defects, telomere shortening, and cellular senescence. Additionally, FKB04 can inhibit tumor growth in a human liver cancer xenograft mouse model (with Huh-7 cells implanted in BALB/c mice). FKB04 can be used in liver cancer research[1].
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FKB04 | 99.98% | FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanism in liver cancer cells, leading to T-loop defects, telomere shortening, and cellular senescence. Additionally, FKB04 can inhibit tumor growth in a human liver cancer xenograft mouse model (with Huh-7 cells implanted in BALB/c mice). FKB04 can be used in liver cancer research. | ||||||||||||||||||||
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Keywords
