Tacc1 - transforming, acidic coiled-coil containing protein 1 Gene
Also Known as 4833447E04Rik; B230378H13Rik
Species: Mus musculus
Summary
Enables nuclear receptor binding activity; peroxisome proliferator activated receptor binding activity; and protein domain specific binding activity. Acts upstream of or within microtubule Cytoskeleton organization; nervous system development; and regulation of microtubule-based process. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; branchial arch; cardiovascular system; central nervous system; and respiratory system. Orthologous to human TACC1 (transforming acidic coiled-coil containing protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Tacc1 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001402841.1 | NP_001389770.1 | transforming acidic coiled-coil-containing protein 1 isoform 3 |
| NM_001402842.1 | NP_001389771.1 | transforming acidic coiled-coil-containing protein 1 isoform 4 |
| NM_001402843.1 | NP_001389772.1 | transforming acidic coiled-coil-containing protein 1 isoform 5 |
| NM_177089.6 | NP_796063.3 | transforming acidic coiled-coil-containing protein 1 long isoform |
| NM_199323.4 | NP_955355.1 | transforming acidic coiled-coil-containing protein 1 short isoform |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables nuclear retinoic acid receptor binding |
IDA
IDA: Inferred from direct assay
|
20078863 | MGI |
| enables nuclear retinoid X receptor binding |
IDA
IDA: Inferred from direct assay
|
20078863 | MGI |
| enables nuclear thyroid hormone receptor binding |
IDA
IDA: Inferred from direct assay
|
20078863 | MGI |
| enables peroxisome proliferator activated receptor binding |
IDA
IDA: Inferred from direct assay
|
20078863 | MGI |
| enables protein domain specific binding |
IPI
IPI: Inferred from physical interaction
|
17920017 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within cell population proliferation |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| acts upstream of or within cerebral cortex development |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| acts upstream of or within interkinetic nuclear migration |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| acts upstream of or within microtubule cytoskeleton organization |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| acts upstream of or within neurogenesis |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| acts upstream of or within regulation of microtubule-based process |
IMP
IMP: Inferred from mutant phenotype
|
17920017 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
transforming acidic coiled-coil-containing protein 1 |
|