2348795-14-0
Chemical Structure
TGFβ1-IN-1
- CAS No.: 2348795-14-0
- Formula:C22H24N2O3
- Molecular Weight:364.44
IUPAC Name: (E)-N-cyclopentyl-3-(3-(4-methoxyphenyl)acrylamido)benzamide
InChIKey: TZERIKHLXBOLFD-SDNWHVSQSA-N
SMILES: O=C(NC1CCCC1)C2=CC=CC(NC(/C=C/C3=CC=C(OC)C=C3)=O)=C2
Biological Activity: TGFβ1-IN-1 (compound 42) is a potent, orally active TGF-β1 inhibitor. TGFβ1-IN-1 inhibits the upregulation of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in liver fibrosis disease studies[1].
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TGFβ1-IN-1 | 99.47% | TGFβ1-IN-1 (compound 42) is a potent, orally active TGF-β1 inhibitor. TGFβ1-IN-1 inhibits the upregulation of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in liver fibrosis disease studies. | ||||||||||||||||||||
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Keywords