25125-92-2
Chemical Structure
Lysine hydroxamate
- CAS No.: 25125-92-2
- Formula:C6H15N3O2
- Molecular Weight:161.20
IUPAC Name: (S)-2,6-diamino-N-hydroxyhexanamide
InChIKey: NZWPVDFOIUKVSJ-YFKPBYRVSA-N
SMILES: NCCCC[C@H](N)C(NO)=O
Biological Activity: Lysine hydroxamate is an amino acid hydroxamate that inhibits the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only L-lysine hydroxamate reduced the growth rate. The inhibition of growth by L-serine hydroxamate could be rapidly reversed by adding L-serine to the bacterial culture or by removing the analog by filtration. This reversal was specific for L-serine. L-alanine, glycine, or adenine had no effect on the inhibited culture. There was no evidence for active transport of the analog.
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Lysine hydroxamate | Lysine hydroxamate is an amino acid hydroxamate that inhibits the growth of Escherichia coli K-12. Of the other amino acid hydroxamates tested, only L-lysine hydroxamate reduced the growth rate. The inhibition of growth by L-serine hydroxamate could be rapidly reversed by adding L-serine to the bacterial culture or by removing the analog by filtration. This reversal was specific for L-serine. L-alanine, glycine, or adenine had no effect on the inhibited culture. There was no evidence for active transport of the analog. | |||||||||||||||||||||
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Keywords
