3023350-32-2

Tubulin polymerization-IN-77 Chemical Structure
3023350-32-2

Chemical Structure

Tubulin polymerization-IN-77

  • CAS No.: 3023350-32-2
  • Formula:C22H19BrF3NO7
  • Molecular Weight:546.29

SMILES: COC1=C(OCO2)C2=C(Br)C3=C1[C@@]([C@]4([H])C5=CC=C(OC)C(OC)=C5C(O4)=O)([H])N(CC3)C(F)(F)F

Biological Activity: Tubulin polymerization-IN-77 (Compound 15c) is a tubulin polymerization inhibitor that exerts anti-glioblastoma activity by inhibiting tubulin polymerization. Tubulin polymerization-IN-77 demonstrates significant blood-brain barrier permeability, effectively inducing G2/M phase arrest and triggering apoptosis in GBM cells, while also significantly inhibiting tumor cell migration[1].

Cat. No. 상품명 Purity 제품 설명 Pricing
HY-170778 		Tubulin polymerization-IN-77 Tubulin polymerization-IN-77 (Compound 15c) is a tubulin polymerization inhibitor that exerts anti-glioblastoma activity by inhibiting tubulin polymerization. Tubulin polymerization-IN-77 demonstrates significant blood-brain barrier permeability, effectively inducing G2/M phase arrest and triggering apoptosis in GBM cells, while also significantly inhibiting tumor cell migration.
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