Med14 - mediator complex subunit 14 Gene

Also Known as ORF1; Crsp2; Gm641; Trap170; 9930001L01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26896

Summary

Predicted to enable transcription coactivator activity. Acts upstream of or within stem cell population maintenance. Part of mediator complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Apr 2022]

Med14 Products (2)

mRNA Protein Name
NM_001048208.1 NP_001041673.1 mediator of RNA polymerase II transcription subunit 14 isoform a
NM_012005.3 NP_036135.3 mediator of RNA polymerase II transcription subunit 14 isoform b
Biological Process GO Annotation Evidence References Source
acts upstream of or within somatic stem cell population maintenance IMP
IMP: Inferred from mutant phenotype
20720539 MGI
Cellular Component GO Annotation Evidence References Source
part of mediator complex IDA
IDA: Inferred from direct assay
15340084 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mediator of RNA polymerase II transcription subunit 14

  • CRSP complex subunit 2

  • cofactor required for Sp1 transcriptional activation subunit 2 (150 kDa)

  • cofactor required for Sp1 transcriptional activation, subunit 2

  • thyroid hormone receptor-associated protein complex 170 kDa component

Orthologs Information

Species Symbol Source ID
Homo sapiens Med14 NCBI NCBI:9282