MYOT - Myot myotilin Gene

Predicted to enable alpha-actinin binding activity and cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in Z disc. Predicted to be active in axon and plasma membrane. Human ortholog(s) of this gene implicated in muscular dystrophy; myofibrillar myopathy 3; and spheroid body myopathy. Orthologous to human MYOT (myotilin). [provided by Alliance of Genome Resources, Apr 2022]