Abcb7 - ATP binding cassette subfamily B member 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 302395

Summary

Predicted to enable ABC-type iron-sulfur cluster transporter activity and protein homodimerization activity. Involved in cellular iron ion homeostasis and negative regulation of Reactive Oxygen Species biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in X-linked sideroblastic anemia with ataxia. Orthologous to human ABCB7 (ATP binding cassette subfamily B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Abcb7 Products (1)

mRNA Protein Name
NM_212518.1 NP_997683.1 iron-sulfur clusters transporter ABCB7, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31511561 RGD
Biological Process GO Annotation Evidence References Source
involved in intracellular iron ion homeostasis IDA
IDA: Inferred from direct assay
31511561 RGD
involved in negative regulation of reactive oxygen species biosynthetic process IMP
IMP: Inferred from mutant phenotype
31511561 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

iron-sulfur clusters transporter ABCB7, mitochondrial

  • ABC transporter 7 protein

  • ATP-binding cassette transporter 7

  • ATP-binding cassette, sub-family B (MDR/TAP), member 7

  • ATP-binding cassette, sub-family B, member 7, mitochondrial

  • ATP-binding cassette, subfamily B (MDR/TAP), member 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00054 ABCB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21467 Abcb7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27985 Abcb7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcb7 NCBI NCBI:22