RPS9 - ribosomal protein S9 Gene

Also Known as S9

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 6203

About RPS9

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,200,858-54,207,647 (from NCBI)

This gene has 13 transcripts (splice variants), 1 gene allele and 190 orthologues. Ubiquitous expression in ovary (RPKM 603.9), bone marrow (RPKM 379.2) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S4P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS9 Products (6)

mRNA Protein Name
NM_001013.4 NP_001004.2 40S ribosomal protein S9 isoform a
NM_001321701.2 NP_001308630.1 40S ribosomal protein S9 isoform a
NM_001321702.2 NP_001308631.1 40S ribosomal protein S9 isoform a
NM_001321704.2 NP_001308633.1 40S ribosomal protein S9 isoform a
NM_001321705.2 NP_001308634.1 40S ribosomal protein S9 isoform b
NM_001321706.2 NP_001308635.1 40S ribosomal protein S9 isoform c
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18420587 GOA
enables structural constituent of ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
enables translation regulator activity IMP
IMP: Inferred from mutant phenotype
18420587 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
18420587 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
involved in translation IMP
IMP: Inferred from mutant phenotype
18420587 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
18420587 GOA
located in cytosolic ribosome IDA
IDA: Inferred from direct assay
23636399 GOA
part of cytosolic small ribosomal subunit IDA
IDA: Inferred from direct assay
8706699 GOA
located in nucleolus IDA
IDA: Inferred from direct assay
18420587 GOA
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
17289661 GOA
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPS9 Protein Structure

Ribosomal_S4

Ribosomal_S4: Ribosomal protein S4/S9 N-terminal domain (7 - 107)

S4

S4: S4 domain (108 - 151)

  • 0
  • 100
  • 194 a.a.
Protein Preferred Names Protein Names

40S ribosomal protein S9

  • small ribosomal subunit protein uS4

RPS9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RPS9 P46781 RPS2 Homo sapiens P15880 30021884
Intra
RPS9 P46781 STAT3 Homo sapiens P40763
Y2H
21988832
Cross: Cross-species interaction Intra: Intraspecies interaction

RPS9 Antibodies

Cat. No. 상품명 신청 Reactivity
HY-P810922 RPS9 Antibody WB, IHC-P, ICC/IF, FC Human, Mouse, Rat

Related Diseases

Diseases Alias
Takayasu Arteritis
  • Aortic Arch Syndrome

  • Pulseless Disease

  • Takayasu'S Arteritis

  • Idiopathic Aortitis

  • Young Female Arteritis

  • Aortic Arch Arteritis

  • Aortic Arches Defect

  • Aortic Arch Defects

  • Takayasu Disease

  • Aortic Arch Syndromes

  • Takayasu'S Disease

  • Ta

  • Obliterative Aortitis

  • Aortic Arch Giant-Cell Arteritis

  • Subclavian-Carotid Obstruction Syndrome

  • Idiopathic Medial Aortopathy And Arteriopathy

  • Takayasu Syndrome

  • Obliterative Brachiocephalic Arteritis Syndrome

  • Raeder-Harbitz Syndrome

  • Chronic Subclavian-Carotid Obstruction Syndrome

  • Giant-Cell Aortitis

  • Takayasu Aortitis

  • Nonspecific Aortoarteritis

  • Sclerosing Aortitis And Arteritis

  • Martorell 2 Syndrome

  • Young Female Aortic Arch Arteritis Syndrome

Diamond-Blackfan Anemia
  • Congenital Pure Red Cell Aplasia

  • Aase Syndrome

  • Erythrogenesis Imperfecta

  • Anemia, Diamond-Blackfan

  • Congenital Hypoplastic Anemia

  • Aase-Smith Ii Syndrome

  • Bds

  • Blackfan-Diamond Anemia

  • Congenital Prca

  • Congenital Hypoplastic Anemia, Blackfan-Diamond Type

  • Dba

  • Blackfan - Diamond Syndrome

  • Chronic Constitutional Pure Red Cell Anaemia

  • Anemia Diamond Blackfan Type

  • Anemia Congenital Erythroid Hypoplastic

  • Aregenerative Anemia Chronic Congenital

  • Blackfan Diamond Syndrome

  • Red Cell Aplasia, Pure Hereditary

  • Aase-Smith Syndrome Ii

  • Bda

  • Blackfan Diamond Anemia

  • Blackfan-Diamond Disease

  • Blackfan-Diamond Syndrome

  • Chronic Congenital Agenerative Anemia

  • Congenital Erythroid Hypoplastic Anemia

  • Congenital Hypoplastic Anemia Of Blackfan And Diamond

  • Congenital Pure Red Cell Anemia

  • Hypoplastic Congenital Anemia

  • Inherited Erythroblastopenia

  • Pure Hereditary Red Cell Aplasia

  • Anemia, Hypoplastic, Congenital

  • Anemia Hypoplastic Congenital

  • Fanconi Anemia

  • Constitutional Aplastic Anemia

  • Diamond-Blackfan Anemia 1

  • Aase Smith Syndrome 2

  • Congenital Red Cell Aplasia

  • Red Cell Aplasia Of Infants

  • Pure Red Cell Aplasia Of Infants

  • Congenital Red Cell Aplastic Anaemia

  • Congenital Pure Red Cell Anaemia

  • Congenital Erythroid Hypoplasia

  • Pearson Marrow-Pancreas Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RPS9 RGD RGD:619889
Felis catus RPS9 VGNC VGNC:64762
Mus musculus RPS9 MGD MGI:1924096
Canis familiaris RPS9 VGNC VGNC:45749
Macaca mulatta RPS9 VGNC VGNC:76936
Bos taurus RPS9 VGNC VGNC:34152
Others RPS9 NCBI