3085297-83-9
Chemical Structure
dCK1α-2
Synonym(s): LC-05-004
- CAS No.: 3085297-83-9
- Formula:C24H23ClN6O4
- Molecular Weight:494.93
InChIKey: XIQNTJXNMQHUHV-IBGZPJMESA-N
SMILES: O=C1N([C@@H]2C(NC(CC2)=O)=O)CC3=C1C=CC(C4=NC5=C(Cl)C(CN6CCOCC6)=NN5C=C4)=C3
Biological Activity: dCK1α-2 is an orally active CK1α molecular glue degrader that targets p53 pathway-related targets. dCK1α-2 exhibits anti-tumor efficacy in mouse models and can increase the expression of p53-related genes.[1].
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dCK1α-2 | 98.79% | dCK1α-2 is an orally active CK1α molecular glue degrader that targets p53 pathway-related targets. dCK1α-2 exhibits anti-tumor efficacy in mouse models and can increase the expression of p53-related genes.. | ||||||||||||||||||||
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Keywords