Akap13 - A kinase (PRKA) anchor protein 13 Gene

Also Known as BRX; LBC; Ht31; AKAP-13; AKAP-Lbc; PROTO-LB; PROTO-LBC; 1700026G02Rik; 5730522G15Rik; 5830460E08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 75547

Summary

Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including adenylate cyclase-activating Adrenergic Receptor signaling pathway involved in heart process; cardiac muscle cell differentiation; and regulation of sarcomere organization. Acts upstream of or within regulation of glucocorticoid mediated signaling pathway. Colocalizes with actin filament. Is expressed in several structures, including central nervous system; genitourinary system; great vessel of heart; heart; and sensory organ. Orthologous to human AKAP13 (A-kinase anchoring protein 13). [provided by Alliance of Genome Resources, Apr 2022]

Akap13 Products (1)

mRNA Protein Name
NM_029332.1 NP_083608.1 A-kinase anchor protein 13

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in bone development IMP
IMP: Inferred from mutant phenotype
25892096 MGI
involved in cardiac muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
20139090 MGI
involved in heart development IMP
IMP: Inferred from mutant phenotype
20139090 MGI
acts upstream of or within regulation of glucocorticoid mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
16469733 MGI
involved in regulation of sarcomere organization IMP
IMP: Inferred from mutant phenotype
20139090 MGI
Cellular Component GO Annotation Evidence References Source
colocalizes with actin cytoskeleton IDA
IDA: Inferred from direct assay
20139090 MGI
colocalizes with actin filament IDA
IDA: Inferred from direct assay
20139090 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

A-kinase anchor protein 13

  • type II cAMP-dependent protein kinase anchoring protein Ht31

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00516 AKAP13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akap13 NCBI NCBI:11214