4 Results for "

HPF1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HPF1" in MCE Product Catalog:

HPF1 Human Pre-designed siRNA Set A
HPF1 Human Pre-designed siRNA Set A
Cat. No.: HY-RS06337
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

HPF1 Human Pre-designed siRNA Set A contains three designed siRNAs for HPF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hpf1 Mouse Pre-designed siRNA Set A
Hpf1 Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS22203
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Hpf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hpf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hpf1 Rat Pre-designed siRNA Set A
Hpf1 Rat Pre-designed siRNA Set A
Cat. No.: HY-RS28725
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

Hpf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hpf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
TGF-β/Smad-IN-3
TGF-β/Smad-IN-3
0 Images
Cat. No.: HY-179042
CAS No.: 3100351-69-4
Target:  

TGF-beta/Smad p38 MAPK Phosphodiesterase (PDE)

Research Areas:  

Inflammation/Immunology

TGF-β/Smad-IN-3 (Compound 4w) is an effective TGF-β/Smad inhibitor. TGF-β/Smad-IN-3 exerts anti-pulmonary fibrosis activity by simultaneously inhibiting the TGF-β/Smad and MAPK signaling pathways. TGF-β/Smad-IN-3 significantly inhibits collagen deposition induced by TGF-β1, with its IC50 value being 3.21 μM. TGF-β/Smad-IN-3 has an IC₅₀ of 46.77 nM for the autocrine motility factor (ATX). TGF-β/Smad-IN-3 significantly reduces the expression levels of α-SMA, COL1A1 and FN in TGF-β1-induced CCC-HPF-1 cells, and effectively inhibited TGF-β1-induced cell migration. TGF-β/Smad-IN-3 can be used for the study of pulmonary fibrosis [1].
Assay Types