2 Results for "

NDUFS7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NDUFS7" in MCE Product Catalog:

Art. -Nr.: HY-RS09163
Forschungsgebiete:  

Others

NDUFS7 Human Pre-designed siRNA Set A contains three designed siRNAs for NDUFS7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Art. -Nr.: HY-182242
Target:  

c-Myc

Forschungsgebiete:  

Cancer

AGB-374 is an orally active NDUFS7 inhibitor. AGB-374 destabilizes NDUFS7 protein and inhibits oxidative phosphorylation by targeting mitochondrial complex I. AGB-374 reduces MYC protein levels in colon cancer cells in vivo and delays tumor growth in syngeneic mouse models of colon cancer. AGB-374 synergistically enhances the cytotoxicity of copper chelators against cancer cells. AGB-374 cooperates with copper chelators to downregulate MYC and NDUFS7 protein levels in cancer cells. AGB-374 can be used for the research of colon cancer .