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Neomycin B-d2

" in MedChemExpress (MCE) Product Catalog:
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Framycetin-d2
Framycetin-d2
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Art. -Nr.: HY-17624S
Synonyms: Neomycin B-d2; Fradiomycin B-d2
Framycetin-d2 (Neomycin B-d2) is the deuterium labeled Framycetin (HY-17624). Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 μM. Framycetin, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.
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