2 Results for "

PD-1+mAb

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PD-1+mAb" in MCE Product Catalog:

Ezabenlimab
Ezabenlimab
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Referencia número: HY-P99610
No. CAS: 2249882-54-8
Synonyms: BI-754091

Target:  

PD-1/PD-L1

Áreas de investigación:  

Cancer

Ezabenlimab (BI-754091) is an anti-PD-1 mAb with binding constant Kd value of 6 nM (CHO cells). Ezabenlimab blocks the interaction of PD-1 with PD-L1 and PD-L2. Ezabenlimab increases interferon-γ secretion in T cells, and inhibits tumor growth in vivo [1].
PXB17
PXB17
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Referencia número: HY-158050
Target:  

c-Fms

Áreas de investigación:  

Cancer

PXB17 can inhibit CSF1R (IC50 = 1.7 nM) by blocking the activation of PI3K/ AKT/mTORC1 signaling. PXB17 is orally effective. PXB17 significantly inhibits the growth of CRC, improves PD-1 mAb efficacy and reduces tumor recurrence in CRC [1].
Assay Types