G6PC1 - G6pc1 glucose-6-phosphatase catalytic subunit 1 Gene

Also Known as G6pc; Psme3; G6Pase

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25634

Summary

Enables glucose-6-phosphatase activity. Involved in several processes, including gluconeogenesis; phosphorylated carbohydrate dephosphorylation; and response to resveratrol. Located in intracellular membrane-bounded organelle. Used to study type 2 diabetes mellitus. Biomarker of fatty liver disease. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human G6PC1 (glucose-6-phosphatase catalytic subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

G6PC1 Products (1)

mRNA Protein Name
NM_013098.2 NP_037230.2 glucose-6-phosphatase catalytic subunit 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables glucose-6-phosphatase activity IDA
IDA: Inferred from direct assay
4303362 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
19579180 RGD
involved in gluconeogenesis IDA
IDA: Inferred from direct assay
4303362 RGD
involved in glucose 6-phosphate metabolic process IDA
IDA: Inferred from direct assay
4303362 RGD
involved in lipid homeostasis IMP
IMP: Inferred from mutant phenotype
9813078 RGD
involved in response to carbohydrate IEP
IEP: Inferred from expression pattern
26883980 RGD
involved in response to food IEP
IEP: Inferred from expression pattern
14988444 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
27366200 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
25943649 RGD
involved in response to resveratrol IEP
IEP: Inferred from expression pattern
27366200 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glucose-6-phosphatase catalytic subunit 1

  • G-6-Pase

  • glucose-6-phosphatase, catalytic subunit

  • proteasome activator subunit 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05191 G6PC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens G6PC1 NCBI NCBI:2538