Krt12 - keratin 12 Gene

Also Known as K12; Krt-12; Krt1-12

Species: Mus musculus

Gene Type: protein coding
Gene ID: 268482

Summary

Predicted to enable structural molecule activity. Involved in cornea development in camera-type eye and morphogenesis of an epithelium. Acts upstream of or within epithelium development. Predicted to be located in intermediate filament. Is expressed in cornea; cornea epithelium; head; lower jaw molar; and upper jaw molar. Human ortholog(s) of this gene implicated in Meesmann corneal dystrophy 1 and corneal dystrophy. Orthologous to human KRT12 (keratin 12). [provided by Alliance of Genome Resources, Apr 2022]

Krt12 Products (1)

mRNA Protein Name
NM_010661.2 NP_034791.2 keratin, type I cytoskeletal 12

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within cornea development in camera-type eye IMP
IMP: Inferred from mutant phenotype
8977471 MGI
involved in cornea development in camera-type eye IMP
IMP: Inferred from mutant phenotype
26758872 MGI
acts upstream of or within epithelium development IMP
IMP: Inferred from mutant phenotype
8977471 MGI
involved in morphogenesis of an epithelium IMP
IMP: Inferred from mutant phenotype
26758872 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

keratin, type I cytoskeletal 12

  • CK-12

  • Keratin, type I cytoskeletal 12 (Cytokeratin 12)

  • cytokeratin-12

  • keratin complex 1, acidic, gene 12

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07435 KRT12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Krt12 NCBI NCBI:3859