Kctd10 - potassium channel tetramerisation domain containing 10 Gene
Also Known as mBACURD3
Species: Mus musculus
Summary
Predicted to enable Notch binding activity and identical protein binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Acts upstream of or within angiogenesis; heart development; and negative regulation of Notch signaling pathway. Part of MKS complex. Is expressed in clavicle; mandible; maxilla; midgut; and rib. Orthologous to human KCTD10 (Potassium Channel tetramerization domain containing 10). [provided by Alliance of Genome Resources, Apr 2022]
Kctd10 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001159941.1 | NP_001153413.1 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 1 |
| NM_026145.4 | NP_080421.2 | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22179047 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within angiogenesis |
IMP
IMP: Inferred from mutant phenotype
|
25401743 | MGI |
| acts upstream of or within heart development |
IMP
IMP: Inferred from mutant phenotype
|
25401743 | MGI |
| acts upstream of or within negative regulation of Notch signaling pathway |
IMP
IMP: Inferred from mutant phenotype
|
25401743 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of MKS complex |
IDA
IDA: Inferred from direct assay
|
22179047 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 |
|