147807-20-3
147807-20-3
Chemical Structure
MD-230254
- CAS No.: 147807-20-3
- Formula:C18H15N3O3
- Molecular Weight:321.33
InChIKey: RBWUKXWSNXXLOG-UHFFFAOYSA-N
SMILES: N#CCCN1N=C(C2=CC=C(OCC3=CC=CC=C3)C=C2)OC1=O
Biological Activity: MD-230254 is a reversible, competitive and selective inhibitor inhibitor of MAO-B with an IC50 value of 1.8 nM. MD-230254 can be used for the study of MAO-B-related neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease[1][2].
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MD-230254 | MD-230254 is a reversible, competitive and selective inhibitor inhibitor of MAO-B with an IC50 value of 1.8 nM. MD-230254 can be used for the study of MAO-B-related neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease. | |||||||||||||||||||||
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References
- [1]. Lebreton L, et al. Selective and potent monoamine oxidase type B inhibitors: 2-substituted 5-aryltetrazole derivatives. J Med Chem. 1995;38(24):4786-4792. [Content Brief]
- [2]. Yoshimoto M, et al. Synthesis and characterization of novel radiofluorinated probes for positron emission tomography imaging of monoamine oxidase B. J Labelled Comp Radiopharm. 2019;62(9):580-587. [Content Brief]
Keywords
