VSTM2L - V-set and transmembrane domain containing 2 like Gene

Also Known as C20orf102; dJ1118M15.2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 128434

About VSTM2L

Cytogenetic location: 20q11.23 Genomic coordinates (GRCh38): 20:37,903,127-37,945,350 (from NCBI)

This gene has 3 transcripts (splice variants), 261 orthologues and 3 paralogues. Biased expression in brain (RPKM 19.4), gall bladder (RPKM 10.9) and 7 other tissues.

Summary

Predicted to enable cell-cell adhesion mediator activity. Involved in negative regulation of neuron apoptotic process. Located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

VSTM2L Products (1)

mRNA Protein Name
NM_080607.3 NP_542174.1 V-set and transmembrane domain-containing protein 2-like protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16713569 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
21393573 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21393573 GOA
located in extracellular region IDA
IDA: Inferred from direct assay
21393573 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VSTM2L Protein Structure

V-set

V-set: Immunoglobulin V-set domain (44 - 149)

  • 0
  • 100
  • 204 a.a.
Protein Preferred Names Protein Names

V-set and transmembrane domain-containing protein 2-like protein

VSTM2L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
VSTM2L Q96N03 CCM2 Homo sapiens Q9BSQ5
Lumier
25814554
Intra
VSTM2L Q96N03 CCM2 Homo sapiens Q9BSQ5
Validated Y2H
25814554
Intra
VSTM2L Q96N03 ATXN1 Homo sapiens P54253
Y2H
16713569
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Bietti Crystalline Corneoretinal Dystrophy

  • BCD

  • Bietti Crystalline Dystrophy

  • Bietti Tapetoretinal Degeneration With Marginal Corneal Dystrophy

  • Bietti Crystalline Retinopathy

  • Bietti'S Crystalline Dystrophy

  • Crystalline Retinopathy

  • Dystrophy, Corneoretinal, Crystalline, Bietti
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15716 VSTM2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VSTM2L MGD MGI:2685537
Canis familiaris VSTM2L VGNC VGNC:48311
Felis catus VSTM2L VGNC VGNC:81257
Bos taurus VSTM2L VGNC VGNC:36844
Rattus norvegicus VSTM2L RGD RGD:1305725
Macaca mulatta VSTM2L VGNC VGNC:97840
Others VSTM2L NCBI