Resf1 - retroelement silencing factor 1 Gene

Also Known as GET; 2810474O19Rik; 6720435I21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67246

Summary

Enables Histone Methyltransferase binding activity. Involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate and positive regulation of DNA methylation-dependent heterochromatin assembly. Acts upstream of or within response to bacterium. Located in nucleus. Part of gamma-tubulin complex. Is expressed in limb; reproductive system; somite; and urinary system. Orthologous to human RESF1 (retroelement silencing factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Resf1 Products (3)

mRNA Protein Name
NM_001289661.1 NP_001276590.1 retroelement silencing factor 1
NM_001289662.1 NP_001276591.1 retroelement silencing factor 1
NM_026054.3 NP_080330.1 retroelement silencing factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone methyltransferase binding IPI
IPI: Inferred from physical interaction
29728365 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IMP
IMP: Inferred from mutant phenotype
29728365 MGI
involved in positive regulation of DNA methylation-dependent heterochromatin formation IMP
IMP: Inferred from mutant phenotype
29728365 MGI
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
Cellular Component GO Annotation Evidence References Source
part of gamma-tubulin complex IMP
IMP: Inferred from mutant phenotype
29728365 MGI
located in nucleus IMP
IMP: Inferred from mutant phenotype
29728365 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

retroelement silencing factor 1

  • likely orthologue of H. sapiens chromosome 12 open reading frame 35 (C12orf35)

  • uncharacterized protein C12orf35 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11851 RESF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Resf1 NCBI NCBI:55196