1428450-95-6
Chemical Structure
Isobutylamido thiazolyl resorcinol
- CAS. Nr.: 1428450-95-6
- Formula:C13H14N2O3S
- Molecular Weight:278.33
IUPAC Name: 5-chloro-4-fluoro-2-hydroxybenzaldehyde
InChIKey: WIDNAJNXDPHROL-UHFFFAOYSA-N
SMILES: O=C(C(C)C)NC1=NC(C2=C(O)C=C(O)C=C2)=CS1
Biological Activity: Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1 μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108 μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Isobutylamido thiazolyl resorcinol | 99.88% | Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1 μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108 μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Vachiramon V, et al. Isobutylamido thiazolyl resorcinol for prevention of UVB-induced hyperpigmentation. J Cosmet Dermatol. 2021 Mar;20(3):987-992. [Content Brief]
- [2]. Roggenkamp D, et al. Effective reduction of post-inflammatory hyperpigmentation with the tyrosinase inhibitor isobutylamido-thiazolyl-resorcinol (Thiamidol). Int J Cosmet Sci. 2021 Jun;43(3):292-301. [Content Brief]
- [3]. Mahalapbutr P, et al. Structural dynamics and susceptibility of isobutylamido thiazolyl resorcinol (ThiamidolTM) against human and mushroom tyrosinases. J Biomol Struct Dyn. 2023;41(21):11810-11817. [Content Brief]
Keywords
