Car9 - carbonic anhydrase 9 Gene

Also Known as Ca9; CAIX; MN/CA9

Species: Mus musculus

Gene Type: protein coding
Gene ID: 230099

About Car9

Chromosome 4: 43,506,966-43,513,729 forward strand.GRCm39:CM000997.3

This gene has 7 transcripts (splice variants), 283 orthologues, 15 paralogues and is associated with 8 phenotypes. Biased expression in stomach adult (RPKM 45.1), duodenum adult (RPKM 29.1) and 6 other tissues.

Summary

Predicted to enable carbonate dehydratase activity. Acts upstream of or within morphogenesis of an epithelium and secretion. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; early embryo; genitourinary system; gut; and heart. Human ortholog(s) of this gene implicated in hepatitis B and renal cell carcinoma. Orthologous to human CA9 (Carbonic Anhydrase 9). [provided by Alliance of Genome Resources, Apr 2022]

Car9 Products (1)

mRNA Protein Name
NM_139305.2 NP_647466.2 carbonic anhydrase 9 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within morphogenesis of an epithelium IMP
IMP: Inferred from mutant phenotype
16217040 MGI
acts upstream of or within secretion IMP
IMP: Inferred from mutant phenotype
16217040 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Car9 Protein Structure

PHA03169

PHA03169: cl27451 (41 - 115)

alpha_CA

alpha_CA: cl00012 (127 - 369)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 437 a.a.
Protein Preferred Names Protein Names

carbonic anhydrase 9

  • CA-IX

  • carbonate dehydratase IX

  • carbonic anhydrase IX

  • membrane antigen MN homolog

Recombinant Car9 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P77585 Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) Q8VHB5-1 (Q32-D390) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01913 Car9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01914 Car9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown