Carbonic Anhydrase 9 Protein, Mouse (HEK293, His)
Based on 1 Customer Validation
The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag.
- Species: Mouse
- Source: HEK293
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The Carbonic Anhydrase 9 protein is responsible for catalyzing the interconversion between carbon dioxide and water, as well as facilitating the conversion of carbonic acid into its dissociated ions, namely bicarbonate and hydrogen ions. Carbonic Anhydrase 9 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Carbonic Anhydrase 9 protein, expressed by HEK293 , with C-His labeled tag.
Background
Carbonic Anhydrase 9 Protein, an enzyme, is involved in maintaining pH homeostasis and regulating tumor microenvironments. Dysregulation of Carbonic Anhydrase 9 Protein has been linked to tumor progression and metastasis. Targeting Carbonic Anhydrase 9 Protein may offer potential therapeutic interventions in cancer by modulating pH levels, disrupting tumor microenvironments, and impairing tumor growth.
Verified Bioactivity
Measured by its esterase activity. The specific activity is >100 pmoles/min/μg.
Technical Parameters
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Species Mouse
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Source HEK293
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Tag C-His
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Accession
Q8VHB5-1 (Q32-D390)
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Molecular Construction
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N-term
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CA9 (Q32-D390)
Accession # Q8VHB5-1 -
His
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C-term
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Protein Length
Extracellular Domain
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Synonyms
CA9; Carbonate Dehydratase IX; Carbonic Anhydrase 9; Carbonic Dehydratase; CAIX; Membrane Antigen MN; MN; P54/58N; Carbonic Anhydrase IX; CA-IX; Renal Cell Carcinoma-Associated Antigen G250; PMW1; RCC-Associated Protein G250; Carbonic Anhydrase; RCC-Assoc
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AA Sequence
QPQGLSGMQGEPSLGDSSSGEDELGVDVLPSEEDAPEEADPPDGEDPPEVNSEDRMEESLGLEDLSTPEAPEHSQGSHGDEKGGGHSHWSYGGTLLWPQVSPACAGRFQSPVDIRLERTAFCRTLQPLELLGYELQPLPELSLSNNGHTVQLTLPPGLKMALGPGQEYRALQLHLHWGTSDHPGSEHTVNGHRFPAEIHVVHLSTAFSELHEALGRPGGLAVLAAFLQESPEENSAYEQLLSHLEEISEEGSKIEIPGLDVSALLPSDLSRYYRYEGSLTTPPCSQGVIWTVFNETVKLSAKQLHTLSVSLWGPRDSRLQLNFRATQPLNGRTIEASFPAAEDSSPEPVHVNSCFTAGD
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Predicted Molecular Mass
43.1 kDa
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Molecular Weight
Approximately 45-53 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by Bis-Tris PAGE.
Product Properties
Solution
Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.
<1 EU/μg, determined by LAL method.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (236 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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