Myrip - myosin VIIA and Rab interacting protein Gene

Also Known as Slac2c; Slac2-c; A230081N12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 245049

Summary

Enables cytoskeletal protein binding activity; protein kinase A binding activity; and small GTPase binding activity. Predicted to be involved in positive regulation of Insulin secretion. Predicted to act upstream of or within vesicle transport along actin filament. Located in several cellular components, including actin cytoskeleton; melanosome; and photoreceptor outer segment. Part of exocyst. Is expressed in several structures, including gut; heart; lung; male reproductive gland or organ; and nervous system. Orthologous to human MYRIP (Myosin VIIA and Rab interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Myrip Products (1)

mRNA Protein Name
NM_144557.5 NP_653140.1 rab effector MyRIP

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin binding IDA
IDA: Inferred from direct assay
12221080 MGI
enables myosin binding IDA
IDA: Inferred from direct assay
12221080 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12590134 MGI
enables protein kinase A binding IPI
IPI: Inferred from physical interaction
17827149 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
12221080 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
12221080 MGI
part of exocyst IDA
IDA: Inferred from direct assay
17827149 MGI
located in melanosome IDA
IDA: Inferred from direct assay
11964381 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
11964381 MGI
located in synapse IDA
IDA: Inferred from direct assay
11964381 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rab effector MyRIP

  • exophilin 8

  • myosin-VIIa- and Rab-interacting protein

  • slp homolog lacking C2 domains c

  • synaptotagmin-like protein lacking C2 domains C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08971 MYRIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Myrip NCBI NCBI:25924