Sod3 - superoxide dismutase 3 Gene

Also Known as ECSODPT

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25352

Summary

Enables superoxide dismutase activity. Involved in blood vessel diameter maintenance; response to copper ion; and response to oxidative stress. Located in several cellular components, including collagen-containing extracellular matrix; extracellular space; and nucleus. Used to study hypertension. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3). [provided by Alliance of Genome Resources, Apr 2022]

Sod3 Products (1)

mRNA Protein Name
NM_012880.2 NP_037012.1 extracellular superoxide dismutase [Cu-Zn] precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables superoxide dismutase activity IDA
IDA: Inferred from direct assay
8643556 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in blood vessel diameter maintenance IMP
IMP: Inferred from mutant phenotype
24322611 RGD
involved in response to copper ion IMP
IMP: Inferred from mutant phenotype
16081273 RGD
involved in response to oxidative stress IEP
IEP: Inferred from expression pattern
15485085 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
16372329 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
8643556 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

extracellular superoxide dismutase [Cu-Zn]

  • EC-SOD

  • Superoxide dimutase 3

  • extracellular superoxide dismutase

  • superoxide dismutase 3, extracellular

  • superoxide dismutase B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-136651 BNTA 99.68% Unkown
HY-RS13561 SOD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17818 Sod3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24287 Sod3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sod3 NCBI NCBI:6649