Slc7a3 - solute carrier family 7 member 3 Gene

Also Known as Cat3; Atrc3; cat-3; Slc7a2

Species: Rattus norvegicus

Gene Type: protein coding

Gene ID: 29485

Summary

Enables L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Involved in amino acid transport and regulation of TOR signaling. Located in plasma membrane. Orthologous to human SLC7A3 (solute carrier family 7 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a3 Products (1)

mRNA	Protein	Name
NM_017217.1	NP_058913.1	cationic amino acid transporter 3

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables L-arginine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9079705	RGD
enables L-lysine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9079705	RGD
enables L-ornithine transmembrane transporter activity	IDA IDA: Inferred from direct assay	9079705	RGD
enables basic amino acid transmembrane transporter activity	IDA IDA: Inferred from direct assay	9079705	RGD

Biological Process GO Annotation	Evidence	References	Source
involved in L-arginine transmembrane transport	IDA IDA: Inferred from direct assay	9079705	RGD
involved in L-arginine transmembrane transport	IMP IMP: Inferred from mutant phenotype	17234578	RGD
involved in lysine transport	IDA IDA: Inferred from direct assay	9079705	RGD
involved in ornithine transport	IDA IDA: Inferred from direct assay	9079705	RGD
involved in regulation of TOR signaling	IMP IMP: Inferred from mutant phenotype	17234578	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
cationic amino acid transporter 3	amino acid transporter, cationic 3 cationic amino acid transporter y+ solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13329	SLC7A3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc7a3	NCBI	NCBI:84889