Akirin2 - akirin 2 Gene

Also Known as FBI1; RGD1307791

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 297968

Summary

Predicted to enable enzyme binding activity; identical protein binding activity; and transcription coregulator activity. Involved in negative regulation of macromolecule metabolic process; positive regulation of cell population proliferation; and positive regulation of endopeptidase activity. Located in nucleus. Part of transcription repressor complex. Orthologous to human AKIRIN2 (akirin 2). [provided by Alliance of Genome Resources, Apr 2022]

Akirin2 Products (1)

mRNA Protein Name
NM_001039914.2 NP_001035003.1 akirin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
18460465 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
18460465 RGD
involved in negative regulation of gene expression IMP
IMP: Inferred from mutant phenotype
18460465 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18460465 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
18460465 RGD
involved in positive regulation of endopeptidase activity IMP
IMP: Inferred from mutant phenotype
18460465 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in nucleus IDA
IDA: Inferred from direct assay
18460465 RGD
part of transcription repressor complex IDA
IDA: Inferred from direct assay
18460465 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

akirin-2

  • fourteen-three-three beta interactant 1

  • fourteen-three-three beta interacting-protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00528 AKIRIN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Akirin2 NCBI NCBI:55122