459853-10-2
459853-10-2
Chemical Structure
LYP-IN-5
- CAS No.: 459853-10-2
- Formula:C27H36N6O
- Molecular Weight:460.61
InChIKey: XGJMAWVIBBKKOB-UHFFFAOYSA-N
SMILES: O=C1NC2=C(C=C1C(N3CCCC4(CCCCC4)C3)C5=NN=NN5C6CCCC6)C=C(C)C=C2
Biological Activity: LYP-IN-5 is a lymphoid tyrosine phosphatase (LYP) inhibitor with an IC50 value of 20.6 μM. LYP-IN-5 enhances the phosphorylation of ZAP70 and ERK1/2 following TCR stimulation, and promotes T cell activation. LYP-IN-5 can be used in the research of autoimmune diseases[1].
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LYP-IN-5 | LYP-IN-5 is a lymphoid tyrosine phosphatase (LYP) inhibitor with an IC50 value of 20.6 μM. LYP-IN-5 enhances the phosphorylation of ZAP70 and ERK1/2 following TCR stimulation, and promotes T cell activation. LYP-IN-5 can be used in the research of autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
