Brinp3 - bone morphogenetic protein/retinoic acid inducible neural specific 3 Gene

Also Known as Fam5c; B830045N13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 215378

Summary

Involved in cellular response to retinoic acid; negative regulation of mitotic cell cycle; and positive regulation of neuron differentiation. Predicted to be located in extracellular region and mitochondrion. Predicted to be active in dendrite; endoplasmic reticulum; and neuronal cell body. Is expressed in central nervous system; olfactory epithelium; and submandibular gland primordium. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human BRINP3 (BMP/retinoic acid inducible neural specific 3). [provided by Alliance of Genome Resources, Apr 2022]

Brinp3 Products (4)

mRNA Protein Name
NM_001145807.1 NP_001139279.1 BMP/retinoic acid-inducible neural-specific protein 3 isoform 1 precursor
NM_001357571.1 NP_001344500.1 BMP/retinoic acid-inducible neural-specific protein 3 isoform 1 precursor
NM_001357572.1 NP_001344501.1 BMP/retinoic acid-inducible neural-specific protein 3 isoform 2
NM_153539.3 NP_705767.3 BMP/retinoic acid-inducible neural-specific protein 3 isoform 1 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within behavior IMP
IMP: Inferred from mutant phenotype
27826231 MGI
involved in cellular response to retinoic acid IDA
IDA: Inferred from direct assay
20025061 MGI
involved in central nervous system neuron differentiation IDA
IDA: Inferred from direct assay
20025061 MGI
acts upstream of or within exploration behavior IMP
IMP: Inferred from mutant phenotype
27826231 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
27826231 MGI
involved in negative regulation of mitotic cell cycle IDA
IDA: Inferred from direct assay
20025061 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
27826231 MGI
acts upstream of or within social behavior IMP
IMP: Inferred from mutant phenotype
27826231 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BMP/retinoic acid-inducible neural-specific protein 3

  • family with sequence similarity 5, member C

  • protein FAM5C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01622 BRINP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brinp3 NCBI NCBI:339479