Pik3r2 - phosphoinositide-3-kinase regulatory subunit 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29741

Summary

Predicted to enable several functions, including 1-phosphatidylinositol-3-kinase regulator activity; enzyme binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in negative regulation of cell migration involved in sprouting angiogenesis. Predicted to be located in focal adhesion and nucleus. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in pancreatic ductal adenocarcinoma. Orthologous to human PIK3R2 (phosphoinositide-3-kinase regulatory subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Pik3r2 Products (1)

mRNA Protein Name
NM_022185.2 NP_071521.2 phosphatidylinositol 3-kinase regulatory subunit beta

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of cell migration involved in sprouting angiogenesis IMP
IMP: Inferred from mutant phenotype
25652288 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphatidylinositol 3-kinase regulatory subunit beta

  • PI3-kinase p85 subunit beta

  • PI3-kinase regulatory subunit beta

  • PI3-kinase subunit p85-beta

  • PI3K regulatory subunit beta

  • phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta

  • phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2

  • ph

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-174976 FHND5032 Inhibitor 99.49% Unkown
HY-RS10537 PIK3R2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21907 Pik3r2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28424 Pik3r2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pik3r2 NCBI NCBI:5296