MAP2K3 - Map2k3 mitogen activated protein kinase kinase 3 Gene

Also Known as Mek3; Mkk3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303200

Summary

Predicted to enable MAP kinase kinase activity and protein kinase binding activity. Involved in several processes, including cellular response to sorbitol; positive regulation of macromolecule metabolic process; and response to ischemia. Located in cytosol. Used to study retinal disease. Human ortholog(s) of this gene implicated in cervical Cancer and restrictive cardiomyopathy. Orthologous to human MAP2K3 (mitogen-activated protein kinase kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

MAP2K3 Products (1)

mRNA Protein Name
NM_001100674.1 NP_001094144.1 dual specificity mitogen-activated protein kinase kinase 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23658158 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to lipopolysaccharide IDA
IDA: Inferred from direct assay
14670949 RGD
involved in cellular response to sorbitol IEP
IEP: Inferred from expression pattern
20550965 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
9779826 RGD
involved in positive regulation of nitric-oxide synthase biosynthetic process IMP
IMP: Inferred from mutant phenotype
10593906 RGD
involved in positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
20550965 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
20550965 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity mitogen-activated protein kinase kinase 3

  • dual specificity mitogen-activated protein kinase kinase 3-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08039 MAP2K3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MAP2K3 NCBI NCBI:5606