Antibacterial agent 12
Antibacterial agent 12, a biaryloxazolidinone analogue, is an antibacterial agent against antibiotic-susceptible and antibiotic-resistant Gram-positive bacteria.
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- CAS No.: 2382921-99-3
- Formule: C22H24FN5O5S
- Masse moléculaire:489.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
>25 μM
Compound: 14a-7
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 31654879] |
Antibacterial agent 12 (compound 14a-7) exhibits a MIC value of 0.125 μg/mL against S.aureus[1].
Antibacterial agent 12 (compound 14a-7) is stable in human liver microsome. Antibacterial agent 12 exhibits lower inhibitory activity against human MAO-A compared to Linezolid[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2382921-99-3
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Masse moléculaire 489.52
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Formule C22H24FN5O5S
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SMILES
CC(NC[C@H]1CN(C2=CC=C(C3=CC=C(/C=N/N4CCS(CC4)(=O)=O)N=C3)C(F)=C2)C(O1)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)